根據一項最新研究發(fā)現(xiàn)，早期應用非創(chuàng)傷性通氣治療拔管后的呼吸衰竭，降低了重癥監(jiān)護室高危患者的死亡率。

一項前瞻性隨機對照臨床試驗包括了162例使用機械通氣的患者，在急性高碳酸血癥康復之后，患者能夠耐受自主呼吸試驗，但是在拔管后出現(xiàn)呼吸衰竭的危險增加。患者在拔管之后被隨機分配接受非創(chuàng)傷性正壓通氣(NPPV)24小時，或者傳統(tǒng)的氧氣治療。

最后研究人員得出結論，非創(chuàng)傷性通氣能夠有利于提高出現(xiàn)慢性呼吸性高碳酸血癥患者的生存率，可以開展新的前瞻性臨床試驗。
 
 
Noninvasive Ventilation in Hypercapnic Patients
 
Early use of noninvasive ventilation averted respiratory failure after extubation and decreased intensive care unit mortality among patients at increased risk, a new study has found.

A prospective randomized controlled trial was conducted in 162 mechanically ventilated patients who tolerated a spontaneous breathing trial after recovery from an acute hypercapnic respiratory failure episode, but had increased risk for respiratory failure after extubation. Patients were randomly allocated after extubation to receive noninvasive positive pressure ventilation (NPPV) for 24 hours or conventional management with oxygen therapy.

The researchers concluded that the beneficial effect of noninvasive ventilation in improving survival of hypercapnic patients with chronic respiratory disorders warrants a new prospective clinical trial.