根據(jù)癲癇在線2005年3月29日發(fā)表的一項最新研究成果發(fā)現(xiàn)：接受過手術(shù)治療的癲癇兒童在總體認(rèn)知發(fā)育方面出現(xiàn)了顯著改善，許多患者癲癇不再發(fā)作。

研究人員隨訪了3歲~7歲的兒童，觀察他們在接受癲癇手術(shù)最初幾年內(nèi)智力的發(fā)育情況。盡管嚴(yán)重癲癇兒童是智力障礙的高風(fēng)險人群，研究結(jié)果顯示這些兒童在手術(shù)之后癲癇不在發(fā)作，智力發(fā)育的更好，而且確實獲得了在手術(shù)之前不具有的能力。

“對那些咨詢他們孩子是否應(yīng)當(dāng)接受癲癇手術(shù)的患兒父母，我們的研究結(jié)果很好的研究回答了這個問題。”通訊作者Ingrid Tuxhorn醫(yī)生說。他一直在德國Bethel癲癇中心進(jìn)行長期生活質(zhì)量的研究。在手術(shù)之后12個月，82%的兒童在發(fā)育上出現(xiàn)了穩(wěn)定的進(jìn)步，3個兒童的智商增加了15點。智商增加僅僅見于那些癲癇不在發(fā)作的兒童。

Tuxhorn醫(yī)生說：“這項對接受過癲癇手術(shù)的學(xué)齡前兒童長期認(rèn)知試驗研究的結(jié)果顯示：癲癇發(fā)作史較短、病因較局限、以及癲癇不在發(fā)作的患者，在成功的手術(shù)之后2~3年認(rèn)知能力提高的機(jī)會更大。現(xiàn)在的問題是提供確定手術(shù)治療理想時間的資料。”Tuxhorn博士與共同作者Hedwig Freitag醫(yī)生是兒童癲癇綜合征以及外科手術(shù)治療教科書的編輯。
 
 
Surgery Reduces Epileptic Seizures
 
Children with epilepsy who underwent surgical treatment showed significant improvements on overall cognitive development and many were left seizure-free, according to a new study published in the March 29, 2005, online edition of Epilepsy.

Researchers followed children aged three to seven years to see how they developed intellectually in the first few years following epilepsy surgery. Although children with severe epilepsy are at high risk for significant mental handicaps, the results showed that those children who became seizure-free after surgery were able to develop better and may actually gain some abilities they did not have before the surgery.

“The questions answered in our study have a significant everyday value for counseling parents whether their child should undergo epilepsy surgery,” said corresponding author Ingrid Tuxhorn, M.D., who is conducting long-term quality-of-life studies on epilepsy at the Bethel Epilepsy Center (Bielefeld, Germany). Twelve months after the surgery, 82% of the children showed stable improvements in development, and three children showed gains of greater than 15 points in their intelligence quotient (IQ). Gains in IQ were only observed in seizure-free children.

“This study on the long-term cognitive outcome of preschool children who had epilepsy surgery shows that children with a shorter duration of epilepsy, more localized etiologies, and a seizure-free outcome have the best chance for improving their cognitive function two to three years after a successful operation,” observed Dr. Tuxhorn. “The question [now] is to provide data to determine ideal timing of surgical treatment.” Dr. Tuxhorn and co-author Hedwig Freitag, M.D., are editors of a book on pediatric epilepsy syndromes and their surgical treatment.