一種新型軟件能夠?qū)uminex公司(Austin, TX, USA)Luminex 200液體檢測(cè)系統(tǒng)獲取的多元數(shù)據(jù)進(jìn)行高級(jí)統(tǒng)計(jì)分析。

MasterPlex QT軟件支持較大的培養(yǎng)皿之間和培養(yǎng)皿內(nèi)的多元數(shù)據(jù)分析。多樣本圖表、三維(3D)圖表和強(qiáng)度地圖能夠幫助分析比較數(shù)據(jù)。這套軟件幫助操作者制作加權(quán)4和5參數(shù)對(duì)數(shù)標(biāo)準(zhǔn)曲線、劑量反應(yīng)曲線和剩余曲線圖。

這套軟件還支持使用商業(yè)檢測(cè)方法獲得的基因表達(dá)分析，包括QuantiGene Plex試劑盒、根據(jù)重復(fù)組標(biāo)準(zhǔn)差自動(dòng)進(jìn)行的無(wú)關(guān)項(xiàng)檢測(cè)，并支持進(jìn)行擁護(hù)自定義的報(bào)告。MasterPlex軟件是由MiraiBio公司(Alameda, CA, USA)開(kāi)發(fā)的，該公司是Hitachi軟件工程美國(guó)公司的分支機(jī)構(gòu)。MiraiBio是Luminex的授權(quán)軟件合作伙伴，已經(jīng)開(kāi)發(fā)了其它軟件產(chǎn)品用于對(duì)Luminex 100、200和IS多功能檢測(cè)平臺(tái)獲得數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。IS系統(tǒng)已經(jīng)被改造用于臨床實(shí)驗(yàn)室的體外診斷檢測(cè)。

Software for Analyzing Multiplexed Data
 
New software aids advanced statistical analysis of multiplexed data generated on the Luminex 200 liquid array detection system of Luminex Corp. (Austin, TX, USA).

The MasterPlex QT software supports both large scale inter- and intra-plate multiplexed data analysis. Multi-sample charts, three-dimensional (3D) depth charts, and intensity maps aid the visualization and comparison of data. The software allows users to generate weighted four- and five-parameter logistics standard curves, dose-response curves, and residual plots.

The software also supports gene expression analysis of data produced using commercial assays, including QuantiGene Plex kits, automatic outlier detection based on standard deviation within a replicate group, and support for customizable reports. The MasterPlex software was developed by MiraiBio (Alameda, CA, USA), a division of Hitachi Software Engineering America, Ltd. MiraiBio is an authorized software partner of Luminex, and has developed other software products for the analysis of data generated on Luminex 100, 200, and IS multiple assay platforms. The IS system is engineered for in-vitro diagnostic applications in clinical laboratories.